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Technical reports

There are currently no technical reports available.

Practical analysis tips 

Some practical analysis tips can be found here.

Research meetings

Presentations of internal research meetings can be viewed here.

Online presentations

An overview of online presentations can be found here.

Supplementary materials



Software related to publications

Several SAS macros/example programs, R packages and WinBugs programs have been written in the process of our research activities. They can be used free of charge. These macros/packages are distributed in the hope that they will be useful, but although thoroughly tested, are WITHOUT ANY WARRANTY.

Macros/packages are available in the following areas:


Software related to books

- Verbeke, G. and Molenberghs, G. (1997) Linear Mixed Models in Practice: A SAS-Oriented Approach. Lecture Notes in Statistics 126. New York: Springer.
- Verbeke, G. and Molenberghs, G. (2000) Linear Mixed Models for Longitudinal Data. New York: Springer-Verlag.
- Molenberghs, G. and Verbeke, G. (2005) Models for Discrete Longitudinal Data. New York: Springer.
- Molenberghs, G. and Kenward, M.G. (2007) Missing Data in Clinical Studies. Chichester: John Wiley & Sons.

  • Datasets
      - demo2: exercise bike data (missing data, 1997)
      - blood: blood pressures (1997 and 2000, case studies)
      - cellprol: (1997, chapter 2)
      - crosover: (1997, chapter 2)
      - growthax: Growth data set used in incomplete data chapters (1997 and 2000)
      - growthgv: Growth curves of girls (case study in 1997; heterogeneity models in 2000)
      - mast01: Mastitis in dairy cattle (2000, sensitivity analysis)
      - milk: milk protein contents (2000, sensitivity analysis)
      - multicnt: (1997, chapter 2)
      - multimpv8: Multiple Imputation
      - press: variceal pressures (1997, case studies)
      - quality: (1997, chapter 2)
      - rats01: rats data (2000, running example)

  • Macros and Programs

- Lin, D.; Shkedy, Z.; Yekutieli, D.; Amaratunga, D.; Bijnens, L. (Eds.) (2012) Modeling Dose-response Microarray Data in Early Drug Development Experiments Using R: Order Restricted Analysis of Microarray Data. Heidelberg: Springer.

- Hens, N.; Shkedy, Z.; Aerts, M.; Faes, C.; Van Damme, P.; Beutels, P. (2012) Modeling Infectious Disease Parameters Based on Serological and Social Contact Data: A Modern Statistical Perspective. New York: Springer.

- Lesaffre E,  Lawson A.B. (2012) Bayesian Biostatistics. New York: Wiley.

Bayesian Biostatistics

- Galecki, A.; Burzykowski. T; (2013) Linear Mixed-Effects Models Using R: A Step-by-Step Approach. New York: Springer.

- Amaratunga, D.; Cabrera, J.; Shkedy, Z. (2014) Exploration and Analysis of DNA Microarray and Other High-Dimensional Data, Wiley Series in Probability and Statistics (2nd edition).  New York: Wiley.

- Kasim, A.; Shkedy, Z.; Kaiser, S.; Hochreiter, S.; Talloen, W. (2016) Applied Biclustering Methods for Big and High Dimensional Data Using R. Chapman & Hall/CRC Biostatistics Series"

Book BiClustering

-Alonso, A., Bigirumurame, T., Burzykowski, T., Buyse, M., Molenberghs, G., Muchene, L., Perualila, N.J., Shkedy, Z., and Van der Elst, W. (2017). Applied Surrogate Endpoint Evaluation with SAS and R. Boca Raton: Chapman & Hall/CRC.

- Bogaerts, K., Komárek, A. and Emmanuel Lesaffre (2017). Survival Analysis with Interval-Censored Data: A Practical Approach with Examples in R, SAS, and BUGS. Boca Raton: Chapman & Hall/CRC.



- Held, L., Hens, N., O'Neill, P., Wallinga, J. (Eds.) (2019) Handbook of Infectious Disease Data Analysis. Chapman and Hall

Handbook of Infectious Disease Data Analysis

  • Last modified 26-11-2019